Principal Scientist Analytical Chemistry

Role purpose:

Within Biologicals Research, the Natural Products and Biomolecular Chemistry group based in Basel-St. Johann, is focusing on the exploring and developing of microbial derived concepts to promote crop health and contribute to the evolution of agricultural practices.

In your role you will applying cutting-edge microbiology and bioengineering techniques to develop novel, sustainable agriculture solutions based on microbial sources. You will lead the development and implementation of analytical technologies to advance the biologicals portfolio derived from microbial and natural product sources, drive innovation in metabolomics approaches, optimize downstream processes, and ensure efficient compound supply from microbial fermentations while providing expert guidance to cross-functional teams, contributing to the successful progression of projects from discovery to development stages.

Accountabilities:

• Lead the analytical platform (HPLC-MS/MS/DAD) in the Natural Products and Biomolecular Chemistry group, driving continuous improvement and efficiency
• Develop and implement advanced metabolomics approaches for early identification and characterization of microbial metabolites, enhancing the discovery pipeline
• Conduct comprehensive characterization of microbial metabolites using MS/MS and NMR techniques
• Design and optimize downstream processing methods for fermentation processes, including the development of efficient purification schemes for high-purity compound isolation
• Provide expert supervision and mentorship to lab associates, fostering their professional growth and ensuring the team's overall scientific excellence
• Lead or Co-lead interdisciplinary projects within the Biologicals research portfolio
• Evaluate and implement new technologies in the analytical field, including the assessment and management of external partnerships to enhance internal capabilities

Syngenta Crop Protection, the largest Syngenta Group unit, leads in sustainable farming solutions, offering innovative products to keep crops healthy while minimizing environmental impact, from planting to harvest.

Syngenta has been ranked as a top employer by Science Magazine and it has been awarded with the "Friendly Work Space" label to all its Swiss sites.

The role is based in Basel St-Johann within the Natural Products and Biomolecular Chemistry unit of Syngenta.

• Ph.D. in a relevant scientific field in Chemistry, Analytical Chemistry or in related disciplines
• Advanced expertise in analytical technologies, with a strong focus on MS and MS/MS data analysis and interpretation
• In-depth understanding and optimization of purification methods of purification technologies for natural products and biomolecules (enzymes, proteins)
• Comprehensive knowledge of microbial metabolite characterization using MS/MS and NMR spectral interpretation
• Thorough understanding of biosynthetic principles in natural product pathways
• Proven track record in analysing and interpreting large analytical datasets
• Experience in leading and managing analytical chemistry in research projects
• Track record of successful collaboration in interdisciplinary scientific teams
• Background in natural product chemistry and biosynthesis as well as experience with advanced data analysis tools for metabolomics data processing is an advantage

We offer a variety of financial and non-financial benefits including:

• We offer a position which contributes to valuable and impactful work in a stimulating and international environment
•  A superb working environment with an open culture and diverse workforce where new ideas are always welcome
• The opportunity to work with and learn from highly qualified and experienced employees and gain scientific and technical excellence
• Learning culture (Together we Grow) and wide range of training options
• You will profit from a competitive pension fund plan, flexible working, attractive bonus system, onsite doctor, fitness room, canteen, and other benefits such as Family friendly initiatives, Child and Family allowance

Please send your complete application with your English CV, diploma and work certificates (if applicable).

Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.